LymphedemaV1, Main, Exploration, bibRecord, 001F01

Differences in limb volume trajectories after breast cancer treatment

Identifieur interne : 001F01 ( Main/Exploration ); précédent : 001F00; suivant : 001F02

Differences in limb volume trajectories after breast cancer treatment

Auteurs : Betty Smoot ; Bruce A. Cooper [États-Unis] ; Yvette Conley [États-Unis] ; Kord Kober [États-Unis] ; Jon D. Levine [États-Unis] ; Judy Mastick [États-Unis] ; Kimberly Topp ; Christine Miaskowski [États-Unis]

Source :

Journal of cancer survivorship : research and practice [ 1932-2259 ] ; 2015.

RBID : PMC:4912957

Descripteurs français

KwdFr :
- Adulte d'âge moyen, Biologie informatique, Femelle, Humains, Lymphoedème (étiologie), Mastectomie (effets indésirables), Risque, Survivants, Tumeurs du sein (), Études longitudinales, Études prospectives.
MESH :
- effets indésirables : Mastectomie.
- étiologie : Lymphoedème.
- Adulte d'âge moyen, Biologie informatique, Femelle, Humains, Risque, Survivants, Tumeurs du sein, Études longitudinales, Études prospectives.

English descriptors

KwdEn :
- Breast Neoplasms (therapy), Computational Biology, Female, Humans, Longitudinal Studies, Lymphedema (etiology), Mastectomy (adverse effects), Middle Aged, Prospective Studies, Risk, Survivors.
MESH :
- adverse effects : Mastectomy.
- etiology : Lymphedema.
- therapy : Breast Neoplasms.
- Computational Biology, Female, Humans, Longitudinal Studies, Middle Aged, Prospective Studies, Risk, Survivors.

Abstract

Purpose

~20% of patients develop lymphedema (LE) following breast cancer (BC) surgery. An evaluation of distinct trajectories of volume change may improve our ability to diagnose LE sooner. The purposes of this study were to identify subgroups of women with distinct trajectories of limb volume changes following BC surgery and to evaluate for phenotypic differences among these classes.

Methods

In this prospective longitudinal study, 380 women were enrolled prior to unilateral BC surgery. Upper limb bioimpedance was measured preoperatively and serially for one year postoperatively. Resistance ratios (RR) were calculated. A RR of >1 indicates affected limb volume > unaffected limb volume. Latent class growth analysis (LCGA) was used to identify classes of women with distinct postoperative RR trajectories. Differences among classes were evaluated using analyses of variance and Chi square analyses.

Results

Three distinct classes were identified: RR <0.95 (37.9%), RR ~1.00 (46.8%), RR >1.05 (15.3%). Patients in the RR >1.05 class were more likely to have diabetes (p=0.036); were more likely to have BC on their dominant side (P<0.001); had higher RR ratios at the preoperative and one-month assessments (P<0.001); and were more likely to be diagnosed with LE (p<0.001).

Conclusions

LCGA is a useful analytic technique to identify subgroups of women who may be at higher risk for the development of LE, based on trajectories of limb volume change after BC surgery.

Implications for cancer survivors

Assessment of preoperative and one-month bioimpedance RRs may allow for the earlier identification of patients who are at higher risk for the development of LE.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912957

DOI: 10.1007/s11764-015-0507-2
PubMed: 26678895
PubMed Central: 4912957

Affiliations:

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Differences in limb volume trajectories after breast cancer treatment</title>
<author><name sortKey="Smoot, Betty" sort="Smoot, Betty" uniqKey="Smoot B" first="Betty" last="Smoot">Betty Smoot</name>
<affiliation><nlm:aff id="A1">School of Medicine, University of California San Francisco, Box 0736, San Francisco, CA, 94143</nlm:aff>
<wicri:noCountry code="subfield">94143</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Cooper, Bruce A" sort="Cooper, Bruce A" uniqKey="Cooper B" first="Bruce A." last="Cooper">Bruce A. Cooper</name>
<affiliation wicri:level="2"><nlm:aff id="A2">School of Nursing, 2 Koret Way, University of California San Francisco, San Francisco, CA 94143</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>School of Nursing, 2 Koret Way, University of California San Francisco, San Francisco</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Conley, Yvette" sort="Conley, Yvette" uniqKey="Conley Y" first="Yvette" last="Conley">Yvette Conley</name>
<affiliation wicri:level="4"><nlm:aff id="A3">School of Nursing, University of Pittsburgh, 3500 Victoria St., Pittsburgh, PA, 15261</nlm:aff>
<orgName type="university">Université de Pittsburgh</orgName>
<country>États-Unis</country>
<placeName><settlement type="city">Pittsburgh</settlement>
<region type="state">Pennsylvanie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kober, Kord" sort="Kober, Kord" uniqKey="Kober K" first="Kord" last="Kober">Kord Kober</name>
<affiliation wicri:level="2"><nlm:aff id="A2">School of Nursing, 2 Koret Way, University of California San Francisco, San Francisco, CA 94143</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>School of Nursing, 2 Koret Way, University of California San Francisco, San Francisco</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Levine, Jon D" sort="Levine, Jon D" uniqKey="Levine J" first="Jon D." last="Levine">Jon D. Levine</name>
<affiliation wicri:level="2"><nlm:aff id="A4">School of Dentistry, University of California San Francisco, Box 0440, San Francisco, CA 94143</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>School of Dentistry, University of California San Francisco, Box 0440, San Francisco</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Mastick, Judy" sort="Mastick, Judy" uniqKey="Mastick J" first="Judy" last="Mastick">Judy Mastick</name>
<affiliation wicri:level="2"><nlm:aff id="A2">School of Nursing, 2 Koret Way, University of California San Francisco, San Francisco, CA 94143</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>School of Nursing, 2 Koret Way, University of California San Francisco, San Francisco</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Topp, Kimberly" sort="Topp, Kimberly" uniqKey="Topp K" first="Kimberly" last="Topp">Kimberly Topp</name>
<affiliation><nlm:aff id="A1">School of Medicine, University of California San Francisco, Box 0736, San Francisco, CA, 94143</nlm:aff>
<wicri:noCountry code="subfield">94143</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Miaskowski, Christine" sort="Miaskowski, Christine" uniqKey="Miaskowski C" first="Christine" last="Miaskowski">Christine Miaskowski</name>
<affiliation wicri:level="2"><nlm:aff id="A2">School of Nursing, 2 Koret Way, University of California San Francisco, San Francisco, CA 94143</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>School of Nursing, 2 Koret Way, University of California San Francisco, San Francisco</wicri:cityArea>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">26678895</idno>
<idno type="pmc">4912957</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912957</idno>
<idno type="RBID">PMC:4912957</idno>
<idno type="doi">10.1007/s11764-015-0507-2</idno>
<date when="2015">2015</date>
<idno type="wicri:Area/Pmc/Corpus">003551</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">003551</idno>
<idno type="wicri:Area/Pmc/Curation">003550</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">003550</idno>
<idno type="wicri:Area/Pmc/Checkpoint">001346</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">001346</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="wicri:Area/PubMed/Corpus">000A98</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000A98</idno>
<idno type="wicri:Area/PubMed/Curation">000A98</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000A98</idno>
<idno type="wicri:Area/PubMed/Checkpoint">000A98</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000A98</idno>
<idno type="wicri:Area/Ncbi/Merge">007C40</idno>
<idno type="wicri:Area/Ncbi/Curation">007C40</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">007C40</idno>
<idno type="wicri:doubleKey">1932-2259:2015:Smoot B:differences:in:limb</idno>
<idno type="wicri:Area/Main/Merge">001F04</idno>
<idno type="wicri:Area/Main/Curation">001F01</idno>
<idno type="wicri:Area/Main/Exploration">001F01</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Differences in limb volume trajectories after breast cancer treatment</title>
<author><name sortKey="Smoot, Betty" sort="Smoot, Betty" uniqKey="Smoot B" first="Betty" last="Smoot">Betty Smoot</name>
<affiliation><nlm:aff id="A1">School of Medicine, University of California San Francisco, Box 0736, San Francisco, CA, 94143</nlm:aff>
<wicri:noCountry code="subfield">94143</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Cooper, Bruce A" sort="Cooper, Bruce A" uniqKey="Cooper B" first="Bruce A." last="Cooper">Bruce A. Cooper</name>
<affiliation wicri:level="2"><nlm:aff id="A2">School of Nursing, 2 Koret Way, University of California San Francisco, San Francisco, CA 94143</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>School of Nursing, 2 Koret Way, University of California San Francisco, San Francisco</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Conley, Yvette" sort="Conley, Yvette" uniqKey="Conley Y" first="Yvette" last="Conley">Yvette Conley</name>
<affiliation wicri:level="4"><nlm:aff id="A3">School of Nursing, University of Pittsburgh, 3500 Victoria St., Pittsburgh, PA, 15261</nlm:aff>
<orgName type="university">Université de Pittsburgh</orgName>
<country>États-Unis</country>
<placeName><settlement type="city">Pittsburgh</settlement>
<region type="state">Pennsylvanie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kober, Kord" sort="Kober, Kord" uniqKey="Kober K" first="Kord" last="Kober">Kord Kober</name>
<affiliation wicri:level="2"><nlm:aff id="A2">School of Nursing, 2 Koret Way, University of California San Francisco, San Francisco, CA 94143</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>School of Nursing, 2 Koret Way, University of California San Francisco, San Francisco</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Levine, Jon D" sort="Levine, Jon D" uniqKey="Levine J" first="Jon D." last="Levine">Jon D. Levine</name>
<affiliation wicri:level="2"><nlm:aff id="A4">School of Dentistry, University of California San Francisco, Box 0440, San Francisco, CA 94143</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>School of Dentistry, University of California San Francisco, Box 0440, San Francisco</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Mastick, Judy" sort="Mastick, Judy" uniqKey="Mastick J" first="Judy" last="Mastick">Judy Mastick</name>
<affiliation wicri:level="2"><nlm:aff id="A2">School of Nursing, 2 Koret Way, University of California San Francisco, San Francisco, CA 94143</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>School of Nursing, 2 Koret Way, University of California San Francisco, San Francisco</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Topp, Kimberly" sort="Topp, Kimberly" uniqKey="Topp K" first="Kimberly" last="Topp">Kimberly Topp</name>
<affiliation><nlm:aff id="A1">School of Medicine, University of California San Francisco, Box 0736, San Francisco, CA, 94143</nlm:aff>
<wicri:noCountry code="subfield">94143</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Miaskowski, Christine" sort="Miaskowski, Christine" uniqKey="Miaskowski C" first="Christine" last="Miaskowski">Christine Miaskowski</name>
<affiliation wicri:level="2"><nlm:aff id="A2">School of Nursing, 2 Koret Way, University of California San Francisco, San Francisco, CA 94143</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>School of Nursing, 2 Koret Way, University of California San Francisco, San Francisco</wicri:cityArea>
</affiliation>
</author>
</analytic>
<series><title level="j">Journal of cancer survivorship : research and practice</title>
<idno type="ISSN">1932-2259</idno>
<idno type="eISSN">1932-2267</idno>
<imprint><date when="2015">2015</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Breast Neoplasms (therapy)</term>
<term>Computational Biology</term>
<term>Female</term>
<term>Humans</term>
<term>Longitudinal Studies</term>
<term>Lymphedema (etiology)</term>
<term>Mastectomy (adverse effects)</term>
<term>Middle Aged</term>
<term>Prospective Studies</term>
<term>Risk</term>
<term>Survivors</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte d'âge moyen</term>
<term>Biologie informatique</term>
<term>Femelle</term>
<term>Humains</term>
<term>Lymphoedème (étiologie)</term>
<term>Mastectomie (effets indésirables)</term>
<term>Risque</term>
<term>Survivants</term>
<term>Tumeurs du sein ()</term>
<term>Études longitudinales</term>
<term>Études prospectives</term>
</keywords>
<keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Mastectomy</term>
</keywords>
<keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr"><term>Mastectomie</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Lymphedema</term>
</keywords>
<keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Breast Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Lymphoedème</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Computational Biology</term>
<term>Female</term>
<term>Humans</term>
<term>Longitudinal Studies</term>
<term>Middle Aged</term>
<term>Prospective Studies</term>
<term>Risk</term>
<term>Survivors</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adulte d'âge moyen</term>
<term>Biologie informatique</term>
<term>Femelle</term>
<term>Humains</term>
<term>Risque</term>
<term>Survivants</term>
<term>Tumeurs du sein</term>
<term>Études longitudinales</term>
<term>Études prospectives</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><sec id="S1"><title>Purpose</title>
<p id="P1">~20% of patients develop lymphedema (LE) following breast cancer (BC) surgery. An evaluation of distinct trajectories of volume change may improve our ability to diagnose LE sooner. The purposes of this study were to identify subgroups of women with distinct trajectories of limb volume changes following BC surgery and to evaluate for phenotypic differences among these classes.</p>
</sec>
<sec id="S2"><title>Methods</title>
<p id="P2">In this prospective longitudinal study, 380 women were enrolled prior to unilateral BC surgery. Upper limb bioimpedance was measured preoperatively and serially for one year postoperatively. Resistance ratios (RR) were calculated. A RR of >1 indicates affected limb volume > unaffected limb volume. Latent class growth analysis (LCGA) was used to identify classes of women with distinct postoperative RR trajectories. Differences among classes were evaluated using analyses of variance and Chi square analyses.</p>
</sec>
<sec id="S3"><title>Results</title>
<p id="P3">Three distinct classes were identified: RR <0.95 (37.9%), RR ~1.00 (46.8%), RR >1.05 (15.3%). Patients in the RR >1.05 class were more likely to have diabetes (p=0.036); were more likely to have BC on their dominant side (P<0.001); had higher RR ratios at the preoperative and one-month assessments (P<0.001); and were more likely to be diagnosed with LE (p<0.001).</p>
</sec>
<sec id="S4"><title>Conclusions</title>
<p id="P4">LCGA is a useful analytic technique to identify subgroups of women who may be at higher risk for the development of LE, based on trajectories of limb volume change after BC surgery.</p>
</sec>
<sec id="S5"><title>Implications for cancer survivors</title>
<p id="P5">Assessment of preoperative and one-month bioimpedance RRs may allow for the earlier identification of patients who are at higher risk for the development of LE.</p>
</sec>
</div>
</front>
</TEI>
<affiliations><list><country><li>États-Unis</li>
</country>
<region><li>Californie</li>
<li>Pennsylvanie</li>
</region>
<settlement><li>Pittsburgh</li>
</settlement>
<orgName><li>Université de Pittsburgh</li>
</orgName>
</list>
<tree><noCountry><name sortKey="Smoot, Betty" sort="Smoot, Betty" uniqKey="Smoot B" first="Betty" last="Smoot">Betty Smoot</name>
<name sortKey="Topp, Kimberly" sort="Topp, Kimberly" uniqKey="Topp K" first="Kimberly" last="Topp">Kimberly Topp</name>
</noCountry>
<country name="États-Unis"><region name="Californie"><name sortKey="Cooper, Bruce A" sort="Cooper, Bruce A" uniqKey="Cooper B" first="Bruce A." last="Cooper">Bruce A. Cooper</name>
</region>
<name sortKey="Conley, Yvette" sort="Conley, Yvette" uniqKey="Conley Y" first="Yvette" last="Conley">Yvette Conley</name>
<name sortKey="Kober, Kord" sort="Kober, Kord" uniqKey="Kober K" first="Kord" last="Kober">Kord Kober</name>
<name sortKey="Levine, Jon D" sort="Levine, Jon D" uniqKey="Levine J" first="Jon D." last="Levine">Jon D. Levine</name>
<name sortKey="Mastick, Judy" sort="Mastick, Judy" uniqKey="Mastick J" first="Judy" last="Mastick">Judy Mastick</name>
<name sortKey="Miaskowski, Christine" sort="Miaskowski, Christine" uniqKey="Miaskowski C" first="Christine" last="Miaskowski">Christine Miaskowski</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001F01 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001F01 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Sante
   |area=    LymphedemaV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     PMC:4912957
   |texte=   Differences in limb volume trajectories after breast cancer treatment
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:26678895" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a LymphedemaV1

This area was generated with Dilib version V0.6.31.
Data generation: Sat Nov 4 17:40:35 2017. Site generation: Tue Feb 13 16:42:16 2024

Serveur d'exploration sur le lymphœdème

Differences in limb volume trajectories after breast cancer treatment

Differences in limb volume trajectories after breast cancer treatment

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration sur le lymphœdème
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.